L-Arginine Alpha Keto Glutarate AAKG

L-Arginine Alpha Keto Glutarate is a form of arginine supplement. Arginine plays a role in the urea cycle, helping to rid the body of excess ammonia. Arginine is also important in protein synthesis. Alpha-Ketoglutarate is another key player in amino acid metabolism, as well as in energy production.

L-Arginine Alpha Keto Glutarate questions
Q. I have read information on L-Arginine Alpha Keto Glutarate from different websites. One site says, "Dramatically Increases Nitric Oxide Production For Increased Muscle Pump! AAKG is arginine alpha-ketoglutarate in a sustained release formula which is pH buffered to ensure maximum absorption. Arginine released into the bloodstream will dramatically increase nitrix oxide production. An increase in nitric oxide may lead to the following benefits: extended and enhanced "muscle pump" after training, improved endurance and recovery time, improved workout capacity, and increased sexual vigor." Is this statement true?
   A. A review of Medline in June 2008 did not reveal any human studies with L-Arginine Alpha Keto Glutarate supplements, therefore we think it is premature to make such statements.

Q. I am 21 years old, and I have been doing serious weight training since i turned 20 (I am a cage fighter as well) and have tried many supplements that boost nitric oxide levels. I get the great pumps and physical advantages of NO boosters like NO-Xplode, BUT it triggers a mental reaction akin to a horribly depressive bi polar episode. The more days in a row that I take the amino acid supplement, or NO-XPLODE, or whatever it may be, the more severely my mental state deteriorates. I have not been able to find any information of this happening to anyone else. Ever. The question is: Have you heard of this before?
   A. NO-Explode has many different amino acids and nutrients such as arginine AKG, rutaecarpine, trimethylglycine, etc. The dosages for some of these supplements is not listed. It is difficult to say which of these substances or which combination is causing the mood changes. Herbs and supplements are potent and misuse can have various mental effects. One option is to reduce the dosage or to take the NO-Xplode product less frequently.

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